COOL-PolarityTE(TM) Regenerates Complex, Hierarchically-Orga
May 1, 2018 12:49:58 GMT
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Post by c2crusher on May 1, 2018 12:49:58 GMT
PolarityTE(TM) Regenerates Complex, Hierarchically-Organized, Corticocancellous Bone in Preclinical Studies
ir.polarityte.com/press-releases/detail/427
SALT LAKE CITY, May 01, 2018 (GLOBE NEWSWIRE) -- PolarityTE™, Inc. (NASDAQ:COOL) announced results demonstrating that the Company’s autologous bone product in development, OsteoTETM, regenerated complex, hierarchically-organized, corticocancellous bone within critically-sized bone defects in standard preclinical large animal models. OsteoTE not only recapitulated the cortical and cancellous architecture of native uninjured bone, but also regenerated bone with function and composition reflective of native bone. The OsteoTE product, which utilizes the subject’s own bone, is prepared and used to treat the defect in less than 24 hours.
OsteoTE Preclinical Results
OsteoTE preclinical results
“The results of these studies using OsteoTE to treat critically-sized bone defects mirror the significance of those seen with SkinTETM, and again confirm that our platform technologies can be successfully used to regenerate complex functional tissues in the most challenging settings,” said Denver M. Lough, M.D., Ph.D., Chairman and Chief Executive Officer of PolarityTE. “We believe there are substantial limitations of the existing treatment options across the numerous applications of OsteoTE, including treatment of bone defects and nonhealing bone within craniomaxillofacial, orthopedic, spine, hand, and foot/ankle specialties. We look forward to continued development and commercialization of products that will change the practice of medicine.”
The Company is planning for an initial limited-market release of OsteoTE in late 2018, targeting specialty markets in a stepwise fashion. The OsteoTE program will follow a similar commercialization process to the Company’s first product – SkinTE™ – a human cellular and tissue-based product derived from a patient’s own skin that results in regeneration of full-thickness (epidermis, dermis and hypodermis), functionally-polarized skin with all the appendages including hair and glands.
Crusher
ir.polarityte.com/press-releases/detail/427
SALT LAKE CITY, May 01, 2018 (GLOBE NEWSWIRE) -- PolarityTE™, Inc. (NASDAQ:COOL) announced results demonstrating that the Company’s autologous bone product in development, OsteoTETM, regenerated complex, hierarchically-organized, corticocancellous bone within critically-sized bone defects in standard preclinical large animal models. OsteoTE not only recapitulated the cortical and cancellous architecture of native uninjured bone, but also regenerated bone with function and composition reflective of native bone. The OsteoTE product, which utilizes the subject’s own bone, is prepared and used to treat the defect in less than 24 hours.
OsteoTE Preclinical Results
OsteoTE preclinical results
“The results of these studies using OsteoTE to treat critically-sized bone defects mirror the significance of those seen with SkinTETM, and again confirm that our platform technologies can be successfully used to regenerate complex functional tissues in the most challenging settings,” said Denver M. Lough, M.D., Ph.D., Chairman and Chief Executive Officer of PolarityTE. “We believe there are substantial limitations of the existing treatment options across the numerous applications of OsteoTE, including treatment of bone defects and nonhealing bone within craniomaxillofacial, orthopedic, spine, hand, and foot/ankle specialties. We look forward to continued development and commercialization of products that will change the practice of medicine.”
The Company is planning for an initial limited-market release of OsteoTE in late 2018, targeting specialty markets in a stepwise fashion. The OsteoTE program will follow a similar commercialization process to the Company’s first product – SkinTE™ – a human cellular and tissue-based product derived from a patient’s own skin that results in regeneration of full-thickness (epidermis, dermis and hypodermis), functionally-polarized skin with all the appendages including hair and glands.
Crusher
